Computation-Guided Design of a Stimulus-Responsive Multienzyme Supramolecular Assembly.
نویسندگان
چکیده
The construction of stimulus-responsive supramolecular complexes of metabolic pathway enzymes, inspired by natural multienzyme assemblies (metabolons), provides an attractive avenue for efficient and spatiotemporally controllable one-pot biotransformations. We have constructed a phosphorylation- and optically responsive metabolon for the biodegradation of the environmental pollutant 1,2,3-trichloropropane.
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ورودعنوان ژورنال:
- Chembiochem : a European journal of chemical biology
دوره 18 20 شماره
صفحات -
تاریخ انتشار 2017